Glucosamine is naturally occurring within the body and is a major component of cartilage. Glucosamine inhibits the enzymes responsible for cartilage breakdown. Chondroitin is a natural component in connective tissue, cartilage and bones where it helps to maintain correct fluid and flexibility. MSM is a compound that contains sulphur, crucial for many body functions and the repair of connective tissues. Cartilage provides cushioning, shock absorption and supports free movement of joints. Over time, constant use and physical trauma can wear away cartilage leading to joint pain, swelling and arthritis. Dietary glucosamine, chondroitin and sulphur levels are typically low, meaning that supplementation may be necessary to increase levels in the body and enable the repair of joint tissues.